| S.No. | Title of Project and Sanction Letter No | Sponsor / Funding Agency | Sanctioned Amount (Rs. in Lakhs) | Tenure / Duration | Supervisor / Principal Investigator / Co-Supervisor | Number of Manpower / Research Fellows | Brief Objective |
|---|---|---|---|---|---|---|---|
| In-Progress | |||||||
| 1. | Ameliorating burn wound management with HNP-1 loaded mesoporous silica nanoparticles: A therapeutic approach SERB/F/9977/2022-2023 | DST SERB | 34.70 | 2023-2026 | Dr. Simran Preet / NA | 1 | To develop a potent topical therapeutic arsenal encompassing a woung healing peptide in a non toxic mesh network targeting the wound environment directly. |
| 2. | Development of a novel antibacterial and antibiofilm coating for biomaterial implants and medical devices 17X/60/2022 | ICMR | 31.30 | 2022 - 2025 | Dr. Avneet Saini / Prof. Kusum Harjai | 1 | • In-silico peptide designing and structural characterization • In-vitro biovalidation of the designed AMPs • Formulation and in-vitro validation of peptide-based biomaterial coating • Establishing the efficacy in in-vivo models |
| 3. | Development and biovalidation of a sustainable Antimicrobial peptide conjugated Collagen Scaffold against infectious bacterial pathogens. S/1373/29 | DST UT | 1.20 | 2022 - 2023 | Dr. Avneet Saini / Dr. Ravneet Kaur | 1 | 1. Extraction and characterization of collagen from the scales of exotic carp 2. Development of Antimicrobial peptide conjugated Fish Collagen scaffold 3. In vitro biovalidation of designed scaffold |
| 4. | Development of a human neutrophil peptide (HNP-1) functionalized antimicrobial catheter against Escheria coli mediated urinary tract infection OMI/7/2020-ECD-I | ICMR | 47.00 | 2020-2023 | Dr. Simran Preet / Prof. Praveen Rishi | 1 | To counter the increasing pathogenesis of E.Coli mediated urinary tract infection post insertion of catheters. Hence, a neutrophil peptide coated catheter development for the purpose of E.Coli eradication in the UTIs. |
| 5. | Aptamer conjugated Teriparatide loaded PLGA/PHBV nanocarriers mediated delivery coners an effective treatment for osteoporosis 00 | DHR | 54.00 | 2023-26 | Dr. Ravi Pratap Barnwal / Prof. Sanjay K Bhadada | 1 | A novel targeted treatment and it development for osteoporosis patients |
| 6. | Evaluation of a colon targeted nisin loaded nanoformulation for anticancer therapy 09/2022/907-915 | DST CHD | 1.50 | 2022- 2023 | Dr. Simran Preet / Dr. Avneet Saini | 1 | To formulate a targeted oral delievery cargo system comprising a novel anticancer peptide |
| 7. | Anticancer therapeutic efficacy of human neutrophil peptide 1 (HNP-1) against 7,12- Dimethylbenzen(a)anthracene (DMBA) induced breast cancer IF200149 | DST INSPIRE | 17.00 | 2021-2026 | Dr. Simran Preet / NA | 1 | To establish the anticancer role of human neutrophil peptide against breast cancer in an in vivo system |
| 8. | In-silico Design and Biovalidation of Novel Peptides/Peptidomimetics: An Advanced Approach Towards Anticancer Regimen 99/20/RUSA/25 | RUSA | 3.50 | 1 year | Dr. Avneet Saini / NA | 1 | 1. In- silico design of novel anticancer peptides/peptidomimetics 2. Structural characterization 3. In - vitro validation |
| 9. | Targeted co-delivery of nisin coated cisplatin enriched solid lipid nanoparticles against murine skin cancer 2019/IF190190 | DST INSPIRE | 17.00 | 2020-2025 | Dr. Simran Preet / NA | 1 | To develop solid lipid nanoparticle of an anticancer peptide for the targeted delivery against skin cancer. |
| 10. | Studies on synergistic potential of human intestinal defensin-5 in conjunction with 5-Fluorouracil against 1,2-dimethylhydrazine dihydrochloride induced colon cancer 2020-7280/PROTEOMICS-BMS | ICMR-Direct SRF | 10.22 | 2021-2023 | Dr. Simran Preet / NA | 1 | To establish strong combinatorial role of HD-5 in conjunction with 5-FU against colon cancer in vivo as well as in vitro. |
| 11. | Diagnostic potential of electrical impedance analyser for bone health detection letterno2 | DST | 32.00 | 2020-23 | Prof. M. L. Garg / | 2 | Diagnostic potential of electrical impedance analyser for bone health detection |
| 12. | Serum Metallothionein level determination using a cost-effective impedimetric immunosensor LetterNo | Seed Fund - FKOL | 1.00 | 2020-21 | Prof. M. L. Garg / | 3 | Serum Metallothionein level determination using a cost-effective impedimetric immunosensor |
| 13. | Insilico identification and experimental validation of novel chemical chaperones for preventing amyloid aggregations and rescue cognitive behavior in Alzheimer’s disease rat model DST/CSRI/2018/70 | DST | 48.00 | 2020-2023 | Dr.Tanzeer Kaur / Dr.Neelima Dhingra | 1 | 1. Identification of lead chaperones in silico. 2. Chemical Synthesis of lead chaperones 3. In vitro activity studies 4. In vivo activity studies |
| 14. | Development of a novel nisin loaded organogel system: A topical therapeutic approach against skin cancer EEQ/2017/000540 | DST SERB | 43.00 | 2017- 2020 | Dr. Simran Preet / NA | 1 | To develop a novel topical dual cargo delivery sytem encompassing both peptide and chemodrug against skin cancer |
| 15. | Evaluation of therapeutic potential of human intestinal alpha defensin 5 against colorectal cancer YSS/2015/001275 | DST SERB | 30.50 | 2015- 2018 | Dr. Simran Preet / NA | 1 | To establish HD-5 as a strong anticolon cancer peptide |
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